Episode 57 - Running on Fumes | Approach to Pancytopenia
Description
Behold the field in which I grow my cells and see that it is barren. It’s out of the frying pan and into the aplastic fire with not a cell in sight. Join Nick, Cale and Bashar without two neutrophils to rub together as we talk about an approach to that most concerning of FBC features - pancytopenia.
TIMESTAMPS
2:22 - Definition of pancytopenia
4:23 - Spurious pancytopenia
6:04 - Cutoffs (arbitrary as usual)
9:43 - Acquired aplastic anaemia
15:30 - Inherited bone marrow failure syndromes
18:52 - Environmental toxins
19:47 - Medications
20:52 - Haematinic deficiencies
25:59 - MDS/Leukaemias
30:54 - Marrow suppression
33:32 - Infiltrative causes
36:45 - Viral causes
38:05 - Approach to pancytopenia
39:06 - History
40:12 - Examination
41:13 - Investigations
42:27 - Liver failure
44:30 - Take Home Messages
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